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Why is it done?

  • Treatment for localized Superficial Urothelial Carcinoma of Bladder and Ureter


How is it done?

  • A Local anaesthetic gel is administered as for a Urethral Catheterisation procedure
  • This is done under a sterile procedure.
  • A 14-16 Fr Indwelling Catheter is placed into your bladder.
  • The pre-made-up Mitomycin solution is installed using strict  administering criteria
  • Usually, 2 vials of 20mg MMC is mixed with Saline to a 50cc volume. You require 40mg.
  • The catheter is then removed
  • The MMC is required to stay in your bladder for 1 hour.
  • Body rotation is not required.
  • WARNING: Any Fevers require urgent attention


 What next?

  • Some local discomfort may be experienced.
  • Your voiding nature will change within the next week
  • You may experience some urinary frequency
  • You could develop a fever requiring urgent attention.
  • Some patients may experience severe pain when/ if the tumour was resected very deep.

NB! Each person is unique and for this  reason, symptoms may vary



  • This will be done every week for 6 weeks
  • 6 weeks after this a check Flexible Cystoscopy will be scheduled as part of your surveillance protocol for your Urothelial carcinoma
  • This may be repeated.
Surveillance Protocol for Superficial Urothelial Carcinoma

Low Grade: Ta, T1 (G1, G2), CIS

· Initially 3 months after the first  resection

· If clear then 9months

· Then annually

High-Risk Low Grade: T1G3 with/out CIS, high volume disease

· This disease may be best treated with a Radical  cystectomy

· 3 monthly Check Cystsocopy for 12 months

· If clear, then 6 monthly for a further 12 months

· If clear then annually for 5-7 years

· My recommendation thereafter would be a 2-yearly cystoscopy with intermittent Urine Cytology

· You fall back to the beginning with any    recurrences

· Please don’t hesitate to direct all further queries to Dr. Schoeman’s rooms.


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Copyright 2019 Dr. Jo Schoeman